Standard
Historical
Last Updated: Aug 16, 2017
Track Document
ASTM F749-98(2002)e1
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
F0749-98R02E01
ASTM|F0749-98R02E01|en-US
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
Standard
F749 Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit>
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BOS Vol. 13.01 Committee F04
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Scope
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices.
1.2 The liquids injected in the rabbits are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.
1.3 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.
1.4 The values stated in SI units are to be regarded as the standard.