Irradiation creep and swelling measurements are reported for Fe-2¼Cr-1Mo after irradiation by fast neutrons over the temperature range 390 to 560°C. Diameter change measurements on thin-walled pressurized tubes in a bainitic condition and density change measurements on rods in a nonstandard condition were made following irradiation in the Experimental Breeder Reactor II. The irradiation creep specimens were irradiated to a fluence of 5.7 × 10²² neutrons (n)/cm² (E > 0.1 MeV) or 30 displacements per atom (dpa) and the swelling specimens were irradiated to a peak fluence of 2.4 × 10²³ n/cm² or 115 dpa. These results have been used as a basis to establish in-reactor creep and swelling correlations for 2¼Cr-1Mo in a bainitic condition. The correlations predict moderate swelling and moderate irradiation enhanced creep at 390°C. The in-reactor creep at 570°C indicates that thermal creep mechanisms become important at this irradiation temperature.