A large volume of atmospheric constituent data is being collected in the global air lanes by specially equipped B-747 aircraft. This NASA program also obtains data from the similarly equipped NASA CV-990 aircraft during dedicated flights as in a recent near pole-to-pole latitude survey mission. Aerosol composition data are also collected with a NASA F-106 aircraft. Present measurements include ozone, carbon monoxide, water vapor, aerosol and condensation nuclei number densities, sulfates, and nitrates. Meteorological and flight parameters are also recorded for use in data analysis. The present aircraft operations obtain data between 6 and 13.5 km from 65 deg N between Europe and the North Pacific, and from 23 deg S over South America and 42 deg S over New Zealand. Typical constituent data from the aircraft operations during the first one and a half years are presented. Instrumentation is discussed.