Over the last decade, the Metallic Materials Properties Development and Standardization (MMPDS) organization has been developing, deploying, and updating the software tools used to analyze uniaxial, tension and compression, and stress-strain datasets. In early 2021, MMPDS initiated an effort to use the method described in ASTM E3076-18, Standard Practice for Determination of the Slope in the Linear Region of a Test Record (superseded), to determine the initial slope of stress-strain curves via the Slope Determination by the Analysis of Residuals (SDAR) methodology. This paper provides the insights gained from the implementation of ASTM E3076-18 in a software tool, Excel for Slope Determination by the Analysis of Residuals (ExSDAR). Based on analysis of a wide range of MMPDS datasets, the authors make several conclusions and recommendations: (1) It is recommended that the results of ASTM E3076-18 analyses be used as guidance, not as pass/fail criteria, and that the wording should be changed to “pass/warn”. (2) For uniaxial stress-strain curves, it is recommended that the slope determined from this method be compared to a method for determining the modulus of the material, such as that described in ASTM E111, Standard Test Method for Young's Modulus, Tangent Modulus, and Chord Modulus, or ASTM E1875, Standard Test Method for Dynamic Young's Modulus, Shear Modulus, and Poisson's Ratio by Sonic Resonance, if available. (3) It is recommended that the resolution data quality metric be reviewed for the potential to provide incorrect results based on the results of this study.