The adhesion and spreading of impacting spray droplets on leaf surfaces for pesticide applications depend on leaf surface roughness as well as the type and concentration of adjuvants contained in the spray solution. Quantifying and relating the effects of surface roughness and adjuvants can improve pesticide spray applications and modeling. This paper presents a preliminary study relating quantified leaf surface roughness to spray deposition and spreading for spray solutions containing different classes and concentrations of adjuvants. A 3D optical surface profiler and the areal roughness parameter for roughness height, S_a , were used to quantify surface roughness for different leaf types ranging in wettability from very easy to very difficult to wet (contact angles between 35° and 160°) and roughness from smooth to very rough. Spray solutions were composed of distilled water and adjuvant concentrations of 0.0, 0.10, 0.25, 0.50, 0.75, and 1.00% (v/v). The adjuvants tested were a crop oil concentrate, a modified seed oil, a nonionic surfactant, an oil-nonionic silicone surfactant blend, and organosilicone. Spray droplets were emitted from a streamed monosized droplet generator mounted on a horizontal motion track traveling at a speed of 1.341 m/s. Droplet motion and impacts were recorded with three ultrahigh-speed video cameras and analyzed using 3D motion analysis software. Deposition was determined by comparing droplet volume before and after impact. There was complete deposition for all adjuvant classes on smooth-easy to wet leaves at all concentrations, whereas deposition on rough-hard to wet leaves increased linearly as concentrations increased. On the rough-hard to wet leaves, approximately 70% deposition was achieved for the nonionic and silicone adjuvants at 0.75% and 0.50% concentrations, respectively. Depositions of less than 70% were achieved for the crop oil concentrate, modified seed oil, and oil-silicone adjuvants.