Particulate Debris from Medical Implants: Mechanisms of Formation and Biological Consequences
Editor(s): Kenneth R. St. John
One of the causes or results (or both) of medical implant failure is the release of particulate material debris from the device because of wear, physical deterioration, or chemical attack by the harsh physiological environment. STP 1144 examines tissue response to particles of implant material in order to identify factors, such as materials selection, surgical protocol, implant design, or postoperative prophylactic drug treatment, that might limit debris generation or moderate the tissue response.
19 peer-reviewed papers written by principal researchers in the field are divided into two sections: clinical experience with the generation of material debris from implants; and in vitro and in vivo models for the clinical situation and methods for generating and characterizing wear debris particles that may be used in laboratory models. For medical implant designers/orthopaedics, orthopaedic surgeons, medial libraries, and biomaterials researchers.
Table of Contents
KR St. John
IC Clarke, P Campbell, N Kossovsky
SB Goodman, VL Fornasier
P Campbell, S Nasser, N Kossovsky, HC Amstutz
JJ Jacobs, RM Urban, F Schajowicz, J Gavrilovic, JO Galante
M Jasty, WJ Maloney, WH Harris, JO Galante, JJ Callaghan
N Kossovsky, K Liao, A Gelman, PA Campbell, HC Amstutz, GAM Finerman, S Nasser, BJ Thomas
BN Stulberg, M Schickendantz, K Merritt, TW Bauer
BN Stulberg, RJ de Swart, SI Reger, K Easley
JH Boss, I Shajrawi, M Soudry, DG Mendes
SB Goodman, RC Chin, SS Chiou, JS Lee
JM Cuckler, J Mitchell, DG Baker, P Ducheyne, V Imonitie, HR Schumacher
MD Lazarus, JM Cuckler, J Mitchell, HR Schumacher, DG Baker, P Ducheyne, V Imonitie
SR Goldring, NE Bennett, MJ Jasty, J-T Wang
J Emmanual, JG Emmanual, AK Hedley
N Kossovsky, D Feng, D Millett, PA Campbell
P Kovacs, JA Davidson, K Daigle
GH Buchhorn, H-G Willert, M Semlitsch, R Schoen, S Steinemann, M Schmidt
ND Macon, JE Lemons, KMW Niemann
PE Greis, HI Georgescu, FH Fu, CH Evans