In this experimental analysis, fabrication and characterization of biocomposites derived from starch-glycerol resin and sisal fiber have been done using the wet hand lay-up technique. Fibers having different weight percentage and 2–3-mm length have been taken for the investigation. The surface of fibers was treated with sodium hydroxide (NaOH) to improve the interphase bonding. The mechanical tests of composites were investigated in accordance with ASTM standards. Various other tests that were conducted include water absorption, thermal analysis, and scanning electron microscopy (SEM). The main drawback of natural composite is its poor water absorption property, which has been checked here by the epoxy coating. The results of the tests reveal a significant improvement in overall properties of biocomposite when compared with the neat starch matrix.