MONOGRAPH Published: 08 December 2014
MONO62014000510

Chapter 10 | Chapter 10 | Synthetic Bone Graft Substitutes: Basic Information for Successful Clinical Use

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Bone grafting techniques are used in many fields of surgery including orthopedic and trauma surgery, periodontal surgery, and maxillofacial surgery. The need to replace bone lost as a result of chronic disease, infection, or trauma is clear. In response to this need, the field has expanded considerably since synthetic substitutes were first used to supplement or replace autologous or allogeneic bone grafting. The number of choices continues to increase as new materials are developed, but in many clinical situations the rationale for selecting one material over another material remains unclear. This is in part due to the lack of information on basic bone biology as it applies to implant materials in general and to a particular clinical application. The purpose of this chapter is to introduce the variety of synthetic bone graft materials currently available, discuss some of the new materials under development, and provide a biological rationale for the outcome when these materials are used clinically in orthopedics.

Author Information

Boyan, Barbara, D.
Virginia Commonwealth University, Richmond, VA, US
Cohen, David, J.
Virginia Commonwealth University, Richmond, VA, US
Schwartz, Zvi
Virginia Commonwealth University, Richmond, VA, US University of Texas Health Science Center at San Antonio, San Antonio, TX, US
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Details
Developed by Committee: F04
Pages: 219–250
DOI: 10.1520/MONO62014000510
ISBN-EB: 978-0-8031-7061-2
ISBN-13: 978-0-8031-7060-5