This study proposes a new blasting method to adjust the distribution of the explosive stress field by modifying the columnar charge section’s spatial position between holes, ensuring the blasting effect while efficiently utilizing explosive energy. Visualization analysis was conducted on the axial Mises stress field of single and double-hole columnar charges using the fundamental principles of blasting impact dynamics. The study focused on examining the distribution law of the axial Mises stress field near the borehole of single-hole columnar charges and between the boreholes of double-hole columnar charges. For the first time, a quantitative zoning of the damage area between holes was performed by combining model experiments with fractal theory. The research explored the impact of five different spatial positions of cylindrical charges, all having the same dosage—namely, explosive recombination degrees of 1, 0.75, 0.5, 0.25, and 0—on the damage and failure characteristics between holes in the specimen. Numerical simulations were carried out on five different charge structures with the same quantity using numerical calculation software. This aimed to investigate the influence of explosive spatial position on the distribution characteristics of the explosion stress field and interhole damage. When the overlap degree of the explosive is 0.5, the damage in each area of the longitudinal and transverse cutting between the holes is the greatest. The distribution of the peak Mises stress contour lines of Mises between the holes is more uniform, and the gradient of the peak Mises stress change of Mises in the center line unit between the holes is the smallest. Adjusting the spatial position of the columnar charge allows for the full utilization of the explosive stress wave and the effect of explosive gas.